An awkward twentysomething begins to undergo some strange physical changes after a weekend tryst — with a ghost — in this charmingly lo-fi, supernaturally-tinged comedy-drama.

On a weekend trip to the Hamptons with friends, Ruth (Lindsay Burdge) encounters a mysterious ghost (Peter Vack) haunting the guest house. One thing leads to another and they find themselves in the throes of an unexpected one-night stand. Soon, Ruth begins suffering from a bizarre sexually-transmitted disease that leaves doctors and friends confused and frightened. As her body and social connections begin to disintegrate, she must find a way to reconcile her condition with the world around her, or risk losing herself to a void from which she may never emerge.